O.C. Begentas, D. Koc, N. Kayali Sendur, P. Besarat, S. Ezgin, M. Temel, H.A. Tokcaer Bora, and E. Kiris (2023). 'Generation and characterization of human induced pluripotent stem cell line METUi002-A from a patient with primary familial brain calcification (PFBC) carrying a heterozygous mutation (c.687dupT (p.Val230CysfsTer28)) in the SLC20A2 gene'. Stem Cell Res. 2023 Oct 18:72:103226. doi: 10.1016/j.scr.2023.103226.

S. Yanpallewar, F. Tomassoni-Ardori, M. E. Palko, Z. Hong, E. Kiris, J. Becker, G. Fulgenzi and L. Tessarollo (2022). “TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior. Translational Psychiatry 12, 111. https://doi.org/10.1038/s41398-022-01869-2

O.C. Begentas, D. Koc, and E. Kiris (2022). "Establishment of Human Induced Pluripotent Stem Cells from Multiple Sclerosis Patients". Methods in Molecular Biology. doi: 10.1007/7651_2021_453

E. Kiris (2021). 'Human induced pluripotent stem cell-based models for studying sex-specific differences in neurodegenerative diseases'. Advances in Experimental Medicine and Biology. https://doi.org/10.1007/5584_2021_683.

E. Sen, K.P. Kota, R.G. Panchal, S. Bavari, and E. Kiris (2021). "Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity". Frontiers in Pharmacology, Volume 12, 2659, DOI=10.3389/fphar.2021.763950.

O.C. Begentas, D. Koc, S. Yurtogullari, M. Temel, K.C. Akcali, S. Demirkaya, and E. Kiris (2021). "Generation and characterization of human induced pluripotent stem cell line METUi001-A from a 25-year-old male patient with relapsing-remitting multiple sclerosis". Stem Cell Research, Volume 53, 102370, https://doi.org/10.1016/j.scr.2021.102370.

J. Konstantinovic, E. Kiris, K. Kota, J. Kugelman-Tonos, M. Videnovic, L. H. Cazares, N. Terzic, T. Z. Verbic, M. Zlatovic, B. Andjelkovic, A. J. Duplantier, S. Bavari and B. A. Solaja (2018). New Steroidal 4-Aminoquinolines Antagonize BoNT/A in Mouse Embryonic Stem Cell Derived Motor Neurons in Post-intoxication Model. Journal of Medicinal Chemistry. 61(4):1595-1608. doi: 10.1021/acs.jmedchem.7b01710.


Y.C. Tsai, A. Kotiya, E. Kiris, M. Yang, S. Bavari, L. Tessarollo, G.A. Oyler, A.M. Weissman (2017). "The deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication". Proceedings of the National Academy of Sciences. 114(26):E5158-E5166.

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M.C. Choi, P. J. Chung, C. Song, H. P. Miller, E. Kiris, Y. Li, L. Wilson, S.C. Feinstein, and C. R. Safinya (2017). "Paclitaxel Suppresses Tau-Mediated Microtubule Bundling". Biochimica et Biophsica Acta (BBA)-General Subjects, 1861(1 Pt A):3456-3463. doi: 10.1016/j.bbagen.2016.09.011.


S. Puverel*, E. Kiris*, S. Singh, K.D. Klarmann, V. Coppola, J. Keller and L. Tessarollo (2016). "RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells". Oncotarget, 2016 Dec 20;7(51):85109-85123. doi: 10.18632/oncotarget.13198. * Equal Contribution.


E. Kiris, J. C. Burnett, J. E. Nuss, L. M. Wanner, B. D. Peyser, H. T. Du, G. Y. Gomba, K. P. Kota, R. Panchal, R. Gussio, C.D. Kane, L. Tessarollo, and S. Bavari (2015). "Src family kinase inhibitors antagonize the toxicity of multiple serotypes of Botulinum neurotoxin in human embryonic stem cell-derived motor neurons". Neurotoxicity Research, 27:384–398, DOI 10.1007/s12640-015-9526-z. *Selected as the cover illustration for the May 2015 edition of the journal.

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E. Kiris, J. E. Nuss, S. M. Stanford, L. M. Wanner, L. Cazares, M. F. Maestre, H.T. Du, G. Y. Gomba, J. C. Burnett, R. Gussio, N. Bottini, R. Panchal, C. D. Kane, L. Tessarollo, and S. Bavari (2015). "Phosphatase inhibitors function as novel, broad spectrum Botulinum neurotoxin antagonists in mouse and human embryonic stem cell-derived motor neuron-based assays". PLoS One. 2015 Jun 10;10(6):e0129264. doi: 10.1371/journal.pone.0129264.


E. Kiris, J. C. Burnett, C. D. Kane, and S. Bavari (2014). "Recent advances in Botulinum neurotoxin inhibitor development". Current Topics in Medicinal Chemistry;14(18):2044-61.

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K. P. Kota, V. Soloveva, L. M. Wanner, G. Y. Gomba, E. Kiris, R. Panchal, C.D. Kane, and S. Bavari (2014). "A High Content Imaging Assay for Identification of Botulinum Neurotoxin Inhibitors". Journal of Visualized Experiments (93), e51915, doi:10.3791/51915.

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E. Kiris*, T. Wang*, S. Yanpallewar, S. Dorsey, J. Becker, S. Bavari, M.E. Palko, V. Coppola, and L. Tessarollo (2014). "TrkA in vivo function is negatively regulated by ubiquitination". The Journal of Neuroscience, Mar 12;34(11):4090-8. doi: 10.1523/JNEUROSCI.4294-13.2014. *Equal Contribution. *Highlighted as a featured article by the journal.

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E. Kiris, K.P. Kota, J. C. Burnett, V. Soloveva, C.D. Kane, and S. Bavari (2014). "Recent developments in cell-based assays and stem cell technologies for Botulinum neurotoxin research and drug discovery". Expert Review of Molecular Diagnostics. 2014 Mar;14(2):153-68. doi: 10.1586/14737159.2014.867808.


E. Kiris, J. E. Nuss, J. C. Burnett, K. P. Kota, D. C. Koh, L. M. Wanner, E. Torres-Melendez, R. Gussio, L. Tessarollo, and S. Bavari (2011). "Embryonic stem cell derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery". Stem Cell Research, 6, pp 195-205, doi: 10.1016/j.scr.2011.01.002.

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E. Kiris, D. Ventimiglia, M. R. Gaylord, M.E. Sargin, A. Altinok, K. Rose, B.S. Manjunath, M. A. Jordan, L. Wilson and S. C. Feinstein (2011). "Combinatorial Tau Pseudophosphorylation: Markedly different regulatory effects on microtubule assembly and dynamic instability than the sum of the individual parts". Journal of Biological Chemistry. 286, 14257-14270, doi: 10.1074/jbc.M111.219311.


E.Kiris, D. Ventimiglia, S.C. Feinstein (2010). "Quantitative analysis of MAP-mediated regulation of microtubule dynamic instability in vitro-Focus on tau". Methods in Cell Biology 95:481-503. 


M.C.Choi, U. Raviv, H. Miller, M. Gaylord, E. Kiris, D. Ventimiglia, L. Wilson, M.W. Kim, S. Feinstein, C.R. Safinya (2009). "Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: A synchrotron X-ray scattering study". Biophysical Journal.; 97(2):519-27. *Selected as the journal's cover page image; * Highlighted in Faculty of 1000


A. Altinok, E. Kiris, A.J. Peck, S. C. Feinstein, L. Wilson, B.S. Manjunath, and K. Rose (2007). "Model based dynamics analysis in live cell microtubule images". BMC Cell Biol. 8 (Suppl 1): S4.

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M.E. Sargin, A. Altinok, E. Kiris, L. Wilson, S. Feinstein, K. Rose and B.S. Manjunath (2007). "Tracing microtubules in live cell images". Proc. IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI'07), p296-299.


Last Updated:
23/10/2023 - 18:00